Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 356-362 doi: 10.1007/s11684-010-0220-5

Keywords： acute myeloid leukemia     mutations     risk stratification    

expression pattern of mutations coordinated by target repression and promoter hypermethylation in acutemyeloid leukemia

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 627-636 doi: 10.1007/s11684-020-0815-4

Keywords： RUNX1     gene mutation     acute myeloid leukemia     transcriptional repression     DNA methylation    

Chimeric antigen receptor T cell therapies for acute myeloid leukemia

Bin Gu, Jianhong Chu, Depei Wu

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 701-710 doi: 10.1007/s11684-020-0763-z

Keywords： acute myeloid leukemia     CAR T     immunotherapy    

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 685-698 doi: 10.1007/s11684-022-0942-1

Keywords： acute myeloid leukemia     acyl-CoA synthetase long chain family member 5     Wnt3a     palmitoylation     ABT-199    

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 896-908 doi: 10.1007/s11684-022-0944-z

Keywords： acute myeloid leukemia     FGF13     prognosis     immune-related genes     bone marrow niches    

Homoharringtonine is a safe and effective substitute for anthracyclines in children younger than 2 years old with acutemyeloid leukemia

Xiaoxiao Chen, Yanjing Tang, Jing Chen, Ru Chen, Longjun Gu, Huiliang Xue, Ci Pan, Jingyan Tang, Shuhong Shen

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 378-387 doi: 10.1007/s11684-018-0658-4

Keywords： homoharringtonine     acute myeloid leukemia     pediatrics    

Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of

Zhan Su, Fengyu Wu, Weiyu Hu, Xiaodan Liu, Shaoling Wu, Xianqi Feng, Zhongguang Cui, Jie Yang, Zhenguang Wang, Hongzai Guan, Hongguo Zhao, Wei Wang, Chunting Zhao, Jun Peng

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 440-444 doi: 10.1007/s11684-017-0523-x

Keywords： Philadelphia chromosome     acute myeloid leukemia     mass     osteolysis     positron emission tomography    

Venetoclax and low-dose cytarabine induced complete remission in a patient with high-risk acute myeloid

Bingshan Liu, Roshni Narurkar, Madhura Hanmantgad, Wahib Zafar, Yongping Song, Delong Liu

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 593-599 doi: 10.1007/s11684-018-0635-y

Keywords： venetoclax     cytarabine     AML     leukemia    

disease after anti-thymocyte globulin-based haploidentical hematopoietic stem cell transplantation in acutemyeloid leukemia

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 667-679 doi: 10.1007/s11684-019-0702-z

Keywords： acute graft-versus-host disease     chronic graft-versus-host disease     National Institutes of Health consensuscriteria     acute myeloid leukemia     anti-thymocyte globulin    

Homoharringtonine synergy with oridonin in treatment of t(8; 21) acute myeloid leukemia

Weina Zhang, Ying Lu, Tao Zhen, Xinjie Chen, Ming Zhang, Ping Liu, Xiangqin Weng, Bing Chen, Yueying Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 388-397 doi: 10.1007/s11684-018-0624-1

Keywords： AML1–ETO     c-KIT     homoharringtonine     oridonin     t(8     21) AML     synergistic effect    

Mutant DNA methylation regulators endow hematopoietic stem cells with the preleukemic stem cell property, a requisite of leukemia initiation and relapse

Yuting Tan,Han Liu,Saijuan Chen

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 412-420 doi: 10.1007/s11684-015-0423-x

Keywords： preleukemic stem cell     acute myeloid leukemia     relapse     DNMT3A    

Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era

Haiyan He, Yang Shen, Yongmei Zhu, Saijuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 204-211 doi: 10.1007/s11684-012-0202-x

Keywords： imatinib     chronic myeloid leukemia     complete cytogenetic response    

Mutation profiling of 16 candidate genes in

Yang Zhang, Fang Wang, Xue Chen, Wenjing Liu, Jiancheng Fang, Mingyu Wang, Wen Teng, Panxiang Cao, Hongxing Liu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 229-237 doi: 10.1007/s11684-018-0616-1

Keywords： leukemia     myeloid     acute     gene     mutation    

^dim/CD34⁺CD117^bri myeloblast-associated gene expression in t(8;21) acutemyeloid leukemia

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi: 10.1007/s11684-021-0836-7

Keywords： t(8     21)(q22     q22) AML     CD34⁺CD117^dim/ CD34⁺CD117^bri cell population     gene expression     prognosis    

Recent advances in myeloid-derived suppressor cell biology

Mahmoud Mohammad Yaseen, Nizar Mohammad Abuharfeil, Homa Darmani, Ammar Daoud

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 232-251 doi: 10.1007/s11684-020-0797-2

Keywords： non-human primates (rhesus macaques)     myeloid-derived pro-inflammatory cells (MDPCs)     autoimmune disorders